interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO TRAC OFF-TARGET1 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.30, R-factor=0.195)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |  13   0   0  13
C |  16   0   0  13
G |  13  96  96  16
T |  54   0   0  54
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updated Sat Aug 2 20:05:42 2025