7rcd_A : 3D-footprint complex

structure name	SECOND STAGE REENGINEERED VARIANT OF I-ONUI TARGETING HUMAN PD1 GENE WITH ACTIVITY ENHANCING SUBSTITUTIONS (I-ONUI_E-HPD1-C)
reference	Ubilla-Rodriguez et al. 'To ? ? ?
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.45, R-factor=0.240)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
reference complex	7rcf_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7rcd_A interface=18,31,35,37,61,65,69,71,129,168,170,172,174,183,185,189,191,213,220,222,224,226,228, resinpwiltgfadaegSfglsilnaryhtRlsfTiMlhnkdksileniqstwkvgiitnNgdhYvtlRvTrfedlkviidhfekyplvtqklgdyklfkqafsvmenkehlkengikelvrikakmnWglndelkkafpeniserplinknipnfkwlagftsgdgSfFvRlRksnvnarvRvQlvfEiSqhirdknlmnslitylgcghiYegnkseRsWlQfRvEkfsdindkiipvfqentligvkledfedwckvaklieekkhltesgldeikkiklnmnk
interface signature	SRTMNYRTWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=17.186 IC/col=1.011 n_of_columns=17

specificity:

A |   0   0   3  27  90  72   6  24   0   4  96   0  96   0   0   0   8
C |   0   0  75   0   0   6  22  24  96  89   0  96   0   0   0  96   3
G |   0  96   6   1   6   6  10  24   0   3   0   0   0  96  96   0  82
T |  96   0  12  68   0  12  58  24   0   0   0   0   0   0   0   0   3

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updated Tue Dec 17 12:58:06 2024