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structure nameSECOND STAGE REENGINEERED VARIANT OF I-ONUI TARGETING HUMAN PD1 GENE WITH ACTIVITY ENHANCING SUBSTITUTIONS
(I-ONUI_E-HPD1-C)
referenceUbilla-Rodriguez et al. 'To ? ? ?
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.45, R-factor=0.240)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
reference complex7rcf_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRTMNYRTWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=17.020 IC/col=1.001 n_of_columns=17 specificity:   
A |   0   0   5  20  89  68  13  24   0   3  96   0  96   0   0   0   6
C |   0   0  82   0   1   6  10  24  96  85   0  96   0   0   0  96   3
G |   0  96   3   3   6  10   8  24   0   3   0   0   0  96  96   0  78
T |  96   0   6  73   0  12  65  24   0   5   0   0   0   0   0   0   9
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updated Fri Sep 13 07:29:23 2024