7rcd_A : 3D-footprint complex

structure name	SECOND STAGE REENGINEERED VARIANT OF I-ONUI TARGETING HUMAN PD1 GENE WITH ACTIVITY ENHANCING SUBSTITUTIONS (I-ONUI_E-HPD1-C)
reference	Ubilla-Rodriguez et al. 'To ? ? ?
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.45, R-factor=0.240)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
reference complex	7rcf_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7rcd_A interface=18,31,35,37,61,65,69,71,129,168,170,172,174,183,185,189,191,213,220,222,224,226,228, resinpwiltgfadaegSfglsilnaryhtRlsfTiMlhnkdksileniqstwkvgiitnNgdhYvtlRvTrfedlkviidhfekyplvtqklgdyklfkqafsvmenkehlkengikelvrikakmnWglndelkkafpeniserplinknipnfkwlagftsgdgSfFvRlRksnvnarvRvQlvfEiSqhirdknlmnslitylgcghiYegnkseRsWlQfRvEkfsdindkiipvfqentligvkledfedwckvaklieekkhltesgldeikkiklnmnk
interface signature	SRTMNYRTWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=16.810 IC/col=0.989 n_of_columns=17

specificity:

A |   4   0   0   0   0   0   0   4   0  24  65   8   0  74   8   0  96
C |  78   0  96  96   0   0   0  13   0  24  15   8   8   0   6  96   0
G |  10  96   0   0   0  96   0  75  96  24   8   6   1   1  78   0   0
T |   4   0   0   0  96   0  96   4   0  24   8  74  87  21   4   0   0

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updated Fri Jan 9 17:22:54 2026