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structure nameFOURTH STAGE REENGINEERED VARIANT OF I-ONUI WITH STABILITY ENHANCING SUBSTITUTIONS
(I-ONUI_E-HPD1-E)
referenceUbilla-Rodriguez et al. 'To ? ? ?
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.23, R-factor=0.193)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
redundant complexes7rcc_D 7rcd_A 7rce_A 7rcg_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSSLRHRTMLNYYWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=18.525 IC/col=0.926 n_of_columns=20 specificity:   
A |   0  24  96   3   3  24  96  88  72  11  24   2   3  96   0  96   0   0   0   3
C |   0  24   0   0   3  24   0   0  10  13  24  88  80   0  96   0   0   0  96  10
G |  96  24   0   0   7  24   0   7   7   7  24   3  10   0   0   0  96  96   0  80
T |   0  24   0  93  83  24   0   1   7  65  24   3   3   0   0   0   0   0   0   3
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Sun Aug 3 18:26:42 2025