7rcf_A : 3D-footprint complex

structure name	FOURTH STAGE REENGINEERED VARIANT OF I-ONUI WITH STABILITY ENHANCING SUBSTITUTIONS (I-ONUI_E-HPD1-E)
reference	Ubilla-Rodriguez et al. 'To ? ? ?
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.23, R-factor=0.193)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
redundant complexes	7rcd_A 7rce_A 7rcg_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7rcf_A interface=18,22,24,26,29,31,35,37,59,61,65,71,129,169,171,173,175,184,186,190,192,214,221,223,225,227,229, resinpwtltgfadaegSfglSiLnRryHtRlsfTiMlhnkdksileniqstwkvgsiLnNgdhYvslvvYrfedlkviidhfekyplitqklgdyklfkqafsvmenkehlkengikelvrikakmnWglndelkkafpevisrerplinknipngkwlagftsgdgSfFvRlRksnvnarvRvQlvfEiSqhirdknlmnslitylgcghiYegnkseRsWlQfRvEkfsdindkiipvfqentligmkledfedwckvaklieekkhltesgldeikkiklnmnkrr
interface signature	SSLRHRTMLNYYWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=19.606 IC/col=0.934 n_of_columns=21

specificity:

A |   2   0   0   0   0   0   0   2   0  24  62   5   0   0  24  67  93   0  24   0   8
C |  87   0  96  96   0   0   0   8   2  24  16   5   8   0  24  19   0   0  24  96  78
G |   5  96   0   0   0  96   0  84  93  24   8   5   0   0  24   8   0   0  24   0   5
T |   2   0   0   0  96   0  96   2   1  24  10  81  88  96  24   2   3  96  24   0   5

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Dendrogram of similar interfaces ?

matrix format

  
  ST----RG--RC--ATVC----DC--YARTRGTAWGSAFC----------RGQG--EASCYTRTWCQGRTEC   L          +----------------------7rcc_D    
                                                                                 +------2 
  SGSTLG--RGKGVT------HCHG----QTRTDC--SANA--KGSCSTTARGQGRG----------RTEAVG   L   !      !       +--------------4yis_A    
                                                                               --3      +-------1 
  SGIG----RGQG--DGTAYCAT--SCVCKGRG----------------------------------------   L   !              +--------------6fb0_A    
                                                                                 ! 
  ------------------------------EC--------DT--------------------KG--------   L   +-----------------------------1r7m_B

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updated Tue Jun 30 07:59:13 2026