interface graph thumbnail
legend  pdf

structure nameFOURTH STAGE REENGINEERED VARIANT OF I-ONUI WITH STABILITY ENHANCING SUBSTITUTIONS
(I-ONUI_E-HPD1-E)
referenceUbilla-Rodriguez et al. 'To ? ? ?
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.23, R-factor=0.193)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
redundant complexes7rcc_D 7rcd_A 7rce_A 7rcg_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSSLRHRTMLNYYWSFRRRQESYRWQRE

Estimated binding specificities ?

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# IC=19.363 IC/col=0.922 n_of_columns=21 specificity:   
A |   5   0   0   0   0   0   0   5   1  24  61   6   0   0  24  70  92   0  24   0   6
C |  82   0  96  96   0   0   0   3   3  24  15  12   7   0  24  17   0   0  24  96  81
G |   6  96   0   0   0  96   0  85  92  24  10   3   0   0  24   6   1   0  24   0   3
T |   3   0   0   0  96   0  96   3   0  24  10  75  89  96  24   3   3  96  24   0   6
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Sat Jan 10 17:19:57 2026