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legend  pdf

structure nameTHIRD STAGE REENGINEERED VARIANT OF I-ONUI WITH SPECIFICITY ENHANCING SUBSTITUTIONS
(I-ONUI_E-HPD1-D)
referenceUbilla-Rodriguez et al. 'To ? ? ?
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.42, R-factor=0.236)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
reference complex7rcf_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSSLHRTMNYVYWSFRRQESYRWQRE

Estimated binding specificities ?

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# IC=17.843 IC/col=0.939 n_of_columns=19 specificity:   
A |   0   0   0   0   0   0   3   0  24  78   4   4   0  24  62  96   0  11   6
C |   0  96  96   0   0   0   2   0  24   6   6  80   0  24  15   0   0  13  84
G |  91   0   0   0  96   0  87  96  24   8   4   6   0  24   6   0   0  60   4
T |   5   0   0  96   0  96   4   0  24   4  82   6  96  24  13   0  96  12   2
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updated Mon Jun 29 02:47:03 2026