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legend  pdf

structure nameTHIRD STAGE REENGINEERED VARIANT OF I-ONUI WITH SPECIFICITY ENHANCING SUBSTITUTIONS
(I-ONUI_E-HPD1-D)
referenceUbilla-Rodriguez et al. 'To ? ? ?
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.42, R-factor=0.236)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
reference complex7rcf_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSSLHRTMNYVYWSFRRQESYRWQRE

Estimated binding specificities ?

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# IC=16.615 IC/col=0.874 n_of_columns=19 specificity:   
A |   2   0   0   0   0   0   4   0  24  70   5   8   0  24  64  96   0  24   5
C |   2  96  96   0   0   0   5   0  24  13   8  73   0  24  14   0   0  24  81
G |  87   0   0   0  96   0  79  96  24   8   5   5   0  24   4   0   0  24   5
T |   5   0   0  96   0  96   8   0  24   5  78  10  96  24  14   0  96  24   5
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updated Sat Aug 2 20:14:58 2025