interface graph thumbnail
legend  pdf

structure nameCAS9:SGRNA:DNA (S. PYOGENES) FORMING A 3-BASE-PAIR R-LOOP
(CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
sourceSTREPTOCOCCUS PYOGENES SEROTYPE M1
experimentNMR
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYKEERRC

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  13   0   0   0  13
C |  13   0   0   0  54
G |  16   0  96  96  13
T |  54  96   0   0  16
scan!

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updated Sat Aug 2 20:22:20 2025