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legend  pdf

structure nameHUMAN DNMT1(729-1600) BOUND TO ZEBULARINE-CONTAINING 12MER DSDNA AND INHIBITOR GSK3735967A
(DNA cytosine-5-methyltransferase 1)
referenceHorton et al. Structure 30 793 2022
sourceHomo sapiens
experimentX-ray (resolution=1.97, R-factor=0.177)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyBAH domain; C5 cytosinespecific DNA methylase;
reference complex6x9j_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Fri Sep 13 07:39:42 2024