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legend  pdf

structure nameCRYO-EM STRUCTURE OF HUMAN DNMT1 (AA:351-1616) IN COMPLEX WITH UBIQUITINATED H3 AND HEMIMETHYLATED DNA ANALOG (CXXC-ORDERED FORM)
experimentNMR
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyBAH domain; C5 cytosinespecific DNA methylase; CXXC zinc finger domain;
redundant complexes3pta_A 6x9i_A 6x9j_A 6x9k_A 7sfc_A 7sfd_A 7sfe_A 7sff_A 7sfg_A 7xib_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKMRFNRHNEKQ

Estimated binding specificities ?

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# IC=3.142 IC/col=0.628 n_of_columns=5 specificity:   
A |  13  24   0   0  13
C |  16  24  96   0  13
G |  13  24   0  96  13
T |  54  24   0   0  57
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updated Sat Jan 10 20:30:00 2026