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structure nameREPLICATION INITIATOR PROTEIN REPE54 AND COGNATE DNA SEQUENCE WITH TERMINAL THREE PRIME PHOSPHATES CHEMICALLY CROSSLINKED (30 MG/ML EDC, 12 HOURS, 2 DOSES).
(RepB family plasmid replication initiator protein)
referenceWard et al.
sourceEscherichia coli
experimentX-ray (resolution=3.28, R-factor=0.204)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=10.996 IC/col=0.611 n_of_columns=18 specificity:   
A |   0   5  24  24  24   0  11  24  24  24  24  11   0   0   0  90   0  73
C |   5   5  24  24  24   0  63  24  24  24  24  11   0   0  96   0  96   7
G |   1  84  24  24  24  96  11  24  24  24  24  12  96   0   0   0   0  11
T |  90   2  24  24  24   0  11  24  24  24  24  62   0  96   0   6   0   5
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updated Sat Aug 2 20:29:30 2025