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structure nameREPLICATION INITIATOR PROTEIN REPE54 AND COGNATE DNA SEQUENCE WITH TERMINAL THREE PRIME PHOSPHATES CHEMICALLY CROSSLINKED (30 MG/ML EDC, 12 HOURS, 2 DOSES).
(RepB family plasmid replication initiator protein)
referenceWard et al.
sourceEscherichia coli
experimentX-ray (resolution=3.28, R-factor=0.204)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=11.789 IC/col=0.655 n_of_columns=18 specificity:   
A |   0   4  62  24  24   0  12  24  24  24  24   8   0   0   0  91   0  75
C |   4   4  10  24  24   0  58  24  24  24  24   4   0   0  96   0  96   4
G |   1  87  16  24  24  96  14  24  24  24  24   8  96   0   0   0   0  12
T |  91   1   8  24  24   0  12  24  24  24  24  76   0  96   0   5   0   5
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updated Fri Jan 9 17:39:50 2026