7u6k_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE. (Replication initiation protein)
reference	Ward et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=2.38, R-factor=0.187)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7u6k_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.195 IC/col=0.724 n_of_columns=21

specificity:

A |   4   4  24  24   0   0   9  24  24  24  24   4   0   0   0  96   0  86  24   0   9
C |   4   7  24  24   0   0   4  24  24  24  24   7   0   0  96   0  96   6  24   4   4
G |   7  81  24  24  96  96  72  24  24  24  24   4  96   0   0   0   0   0  24  92   0
T |  81   4  24  24   0   0  11  24  24  24  24  81   0  96   0   0   0   4  24   0  83

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updated Fri Jan 9 18:07:23 2026