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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.38, R-factor=0.187)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.926 IC/col=0.711 n_of_columns=21 specificity:   
A |  75   0  24   5   0   0   0  96   0  81  24  24  24  24   5   0   0  24  24  11  85
C |   6  96  24   1   0   0   0   0  96   5  24  24  24  24  71  96  96  24  24  70   6
G |  10   0  24   5  96   0  96   0   0   5  24  24  24  24  15   0   0  24  24  10   0
T |   5   0  24  85   0  96   0   0   0   5  24  24  24  24   5   0   0  24  24   5   5
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updated Sat Aug 2 20:51:18 2025