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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.38, R-factor=0.187)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.038 IC/col=0.716 n_of_columns=21 specificity:   
A |  79   0  24   4   0   0   0  96   0  84  24  24  24  24   8   0   0  24  24   8  84
C |   5  96  24   5   0   0   0   0  96   4  24  24  24  24  68  96  96  24  24  80   4
G |   8   0  24   8  96   0  96   0   0   4  24  24  24  24  16   0   0  24  24   4   4
T |   4   0  24  79   0  96   0   0   0   4  24  24  24  24   4   0   0  24  24   4   4
scan!

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updated Tue Dec 17 13:34:09 2024