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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL T-A RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.97, R-factor=0.247)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.512 IC/col=0.739 n_of_columns=21 specificity:   
A |   0   3  70  24   0   0   3  24  24  24  24   0   0   0   0  96   0  73  24   5   3
C |  22   7   7  24   0   0  84  24  24  24  24   0   0   0  96   0  96   3  24   3  77
G |   1  81   5  24  93  96   3  24  24  24  24   0  96   0   0   0   0   9  24  81   3
T |  73   5  14  24   3   0   6  24  24  24  24  96   0  96   0   0   0  11  24   7  13
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updated Mon Jun 29 03:33:41 2026