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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL T-A RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.97, R-factor=0.247)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.619 IC/col=0.744 n_of_columns=21 specificity:   
A |  11   3  24  10   0   0   0  96   0  96  24  24  24  24   3   0   4  24  10   3  80
C |   3  76  24   3   0   0   0   0  96   0  24  24  24  24   3  96  92  24   3  80   0
G |  76  10  24  11  96   0  96   0   0   0  24  24  24  24  87   0   0  24   7   6  16
T |   6   7  24  72   0  96   0   0   0   0  24  24  24  24   3   0   0  24  76   7   0
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updated Tue Dec 17 13:36:50 2024