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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL T-A RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.97, R-factor=0.247)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.658 IC/col=0.746 n_of_columns=21 specificity:   
A |  19   7  24   8   0   0   0  96   0  96  24  24  24  24   8   0   3  24   7   3  77
C |   0  77  24   7   0   0   0   0  96   0  24  24  24  24   0  96  92  24   9  84   1
G |  77   7  24  11  96   0  96   0   0   0  24  24  24  24  88   0   1  24  14   3  18
T |   0   5  24  70   0  96   0   0   0   0  24  24  24  24   0   0   0  24  66   6   0
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updated Fri Jan 9 18:10:22 2026