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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND ASYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.63, R-factor=0.197)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=10.701 IC/col=0.669 n_of_columns=16 specificity:   
A |  11  60  24   0   0  10  24  24  24  24   5   0   1   0  96   0
C |  10  10  24   0   0  65  24  24  24  24   5   0  15  96   0  96
G |  65  11  24  96  96  10  24  24  24  24   6  96   0   0   0   0
T |  10  15  24   0   0  11  24  24  24  24  80   0  80   0   0   0
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updated Fri Jan 9 18:15:22 2026