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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND ASYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceWard et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.63, R-factor=0.197)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=10.782 IC/col=0.674 n_of_columns=16 specificity:   
A |   9  61  24   0   0   9  24  24  24  24   4   0   0   0  96   0
C |   9  13  24   0   0  64  24  24  24  24   4   0  22  96   0  96
G |  69   4  24  96  96  10  24  24  24  24   6  96   1   0   0   0
T |   9  18  24   0   0  13  24  24  24  24  82   0  73   0   0   0
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updated Mon Jun 29 03:39:05 2026