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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SCAFFOLD DUPLEX (21MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN INSERT DUPLEX (10MER) WITH GUEST TAMRA- LABELLED THYMINE AND T-A RICH SEQUENCE.
(Replication initiation protein)
referenceOrun et al. 'To ? ? ?
sourceEscherichia coli K-12
experimentX-ray (resolution=3.02, R-factor=0.235)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRR

Estimated binding specificities ?

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# IC=11.121 IC/col=0.654 n_of_columns=17 specificity:   
A |   0   0   0  96   0  96  24  24  24  24  13   0  24   6  24  13  82
C |   0   0   0   0  96   0  24  24  24  24  20  96  24  64  24  61   1
G |  96   0  96   0   0   0  24  24  24  24  48   0  24  13  24   6  13
T |   0  96   0   0   0   0  24  24  24  24  15   0  24  13  24  16   0
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updated Fri Jan 9 18:17:09 2026