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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF PROTEIN VARIANT REPLICATION INITIATOR PROTEIN REPE54 (L53G,Q54G,E55G) AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.959 IC/col=0.712 n_of_columns=21 specificity:   
A |   1  10  24  24   0   0  10  24  24  24  24   0   0   0   0  96   0  71  24   0   7
C |   5   5  24  24   0   0  69  24  24  24  24   0   0   0  96   0  96  10  24   0  10
G |   0  69  24  24  90  96   5  24  24  24  24   0  96   0   0   0   0   5  24  96   5
T |  90  12  24  24   6   0  12  24  24  24  24  96   0  96   0   0   0  10  24   0  74
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updated Tue Dec 17 13:44:33 2024