interface graph thumbnail
legend  pdf

structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF PROTEIN VARIANT REPLICATION INITIATOR PROTEIN REPE54 (L53G,Q54G,E55G) AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contactlogo
# IC=15.174 IC/col=0.723 n_of_columns=21 specificity:   
A |   0   4  24  24   1   0   9  24  24  24  24   0   0   0   0  96   0  69  24   0   4
C |   5  11  24  24   0   0  67  24  24  24  24   0   0   0  96   0  96  14  24   0   4
G |   0  72  24  24  91  96   4  24  24  24  24   0  96   0   0   0   0   9  24  96   9
T |  91   9  24  24   4   0  16  24  24  24  24  96   0  96   0   0   0   4  24   0  79
scan!

home
updated Fri Jan 9 18:20:24 2026