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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF PROTEIN VARIANT REPLICATION INITIATOR PROTEIN REPE54 (L53G,Q54G,E55G) AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.948 IC/col=0.712 n_of_columns=21 specificity:   
A |  72   0  24  14   0   0   0  96   0  96  24  24  24  24  14   0   0  24  24   9  91
C |   4  96  24  16   0   0   0   0  96   0  24  24  24  24   4  96  96  24  24  64   0
G |   9   0  24   9  96   0  96   0   0   0  24  24  24  24  74   0   0  24  24   9   4
T |  11   0  24  57   0  96   0   0   0   0  24  24  24  24   4   0   0  24  24  14   1
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updated Mon Jun 29 03:44:11 2026