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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF PROTEIN VARIANT REPLICATION INITIATOR PROTEIN REPE54 (L53G,Q54G,E55G) AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.947 IC/col=0.712 n_of_columns=21 specificity:   
A |   0   5  24  24   0   0   5  24  24  24  24   0   0   0   0  96   0  73  24   0   7
C |   5  11  24  24   0   0  67  24  24  24  24   0   0   0  96   0  96  12  24   0  11
G |   0  67  24  24  90  96   5  24  24  24  24   0  96   0   0   0   0  11  24  96  11
T |  91  13  24  24   6   0  19  24  24  24  24  96   0  96   0   0   0   0  24   0  67
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updated Sat Aug 2 21:02:12 2025