7v59_E : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF SPYCAS9-SGRNA-DNA DIMER
experiment	NMR
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7v59_E interface=69,448,489,493,767,892,909,911,912,914,919,959,1034,1105,1106,1215,1238,1329,1331,1333, kkysigldigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrRytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripYyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsFierMtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvsgqgdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarenqTtqkgqknsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdhivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitQrkfdnltkaergglseLdKAgFikrqLvetrqitkhvaqildsrmntkydendklirevkvitlksKlvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdykvydvrkmiakseqeigkatakYffysnimnffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKEspkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashYeklkgspedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkRyTstkevldatlihqsitglyetridlsq
interface signature	RYFMTQLKAFLKYKEEYRRT

Estimated binding specificities ?

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# IC=7.965 IC/col=0.724 n_of_columns=11

specificity:

A |   0   0   0  96  24  24   0   9  11  24  11
C |   0  96  96   0  24  24   0  11  67  24  67
G |  96   0   0   0  24  24  96   9   9  24   9
T |   0   0   0   0  24  24   0  67   9  24   9

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updated Fri Jan 9 18:22:40 2026