7v59_E : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF SPYCAS9-SGRNA-DNA DIMER
experiment	NMR
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7v59_E interface=69,448,489,493,767,892,909,911,912,914,919,959,1034,1105,1106,1215,1238,1329,1331,1333, kkysigldigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrRytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripYyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsFierMtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvsgqgdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarenqTtqkgqknsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdhivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitQrkfdnltkaergglseLdKAgFikrqLvetrqitkhvaqildsrmntkydendklirevkvitlksKlvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdykvydvrkmiakseqeigkatakYffysnimnffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKEspkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashYeklkgspedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkRyTstkevldatlihqsitglyetridlsq
interface signature	RYFMTQLKAFLKYKEEYRRT

Estimated binding specificities ?

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# IC=8.004 IC/col=0.728 n_of_columns=11

specificity:

A |   9  24   9  67   0  24  24   0   0   0   0
C |   9  24   9   9  96  24  24   0   0   0  96
G |  69  24  67   9   0  24  24   0  96  96   0
T |   9  24  11  11   0  24  24  96   0   0   0

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updated Sat Aug 2 21:04:08 2025