interface graph thumbnail
legend  pdf

structure nameCRYO-EM STRUCTURE OF HUMAN DNMT1 (AA:351-1616) IN COMPLEX WITH UBIQUITINATED H3 AND HEMIMETHYLATED DNA ANALOG (CXXC-DISORDERED FORM)
experimentNMR
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyBAH domain; C5 cytosinespecific DNA methylase;
redundant complexes7xi9
reference complex7xi9_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKMRFNRHNEKQ

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |  16  24   0   0  13
C |  13  24  96   0  16
G |  13  24   0  96  13
T |  54  24   0   0  54
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updated Fri Jan 9 19:04:40 2026