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structure nameCRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN WITH C-TERMINAL EXTENSION (DBD-CTE) HOMODIMER BOUND TO DR1 RESPONSE ELEMENT
referenceChen et al. 'Nucleic 51 1443 2023
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=?)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
reference complex7xv6_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKKRR/EKKR

Estimated binding specificities ?

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# IC=11.613 IC/col=0.968 n_of_columns=12 specificity:   
A |   9   0  96   0   0   7  24  14   0  88   0   0
C |   7   0   0  96  96  23  24   7   0   0  96  96
G |  14  96   0   0   0   7  24   7  96   7   0   0
T |  66   0   0   0   0  59  24  68   0   1   0   0
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updated Fri Aug 1 01:00:24 2025