7xv6_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN WITH C-TERMINAL EXTENSION (DBD-CTE) HOMODIMER BOUND TO DR1 RESPONSE ELEMENT (NR2C2 protein)
reference	Chen et al. 'Nucleic 51 1443 2023
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	7xv6_AB 7xv8_AB
redundant complexes	7xv8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xv6_B interface=23,26,30,31, vveycvvcgdkasgrhygavscEgcKgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs
interface signature	EKKR

Estimated binding specificities ?

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# IC=4.887 IC/col=0.977 n_of_columns=5

specificity:

A |   0   0   0   0  38
C |   0   0  20  96  20
G |  96  96   0   0  19
T |   0   0  76   0  19

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Dendrogram of similar interfaces ?

matrix format

  
  --EAKG--RTRT--RT                                 +4umm_E    
                                               +---1 
  CAECKG--KGRG----   L            +------------2   +1cit_A    
                                  !            ! 
  --ECKGAG--RG----   L     +------4            +---4ond_A    
                           !      ! 
  --ECKG----RA----   L     !      !           +----5krb_G    
                         +-5      +-----------3 
  --ECKGAG--KTRG--   L   ! !                  +----4aa6_B    
                       --6 ! 
  --EAKG--KTRG----   L   ! +-----------------------4umm_A    
                         ! 
  ----KGVT--RG----   L   +------------------------2c7a_B

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updated Sat Jan 10 20:38:23 2026