7xv6_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN WITH C-TERMINAL EXTENSION (DBD-CTE) HOMODIMER BOUND TO DR1 RESPONSE ELEMENT (NR2C2 protein)
reference	Chen et al. 'Nucleic 51 1443 2023
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	7xv6_AB 7xv8_AB
redundant complexes	7xv8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xv6_B interface=23,26,30,31, vveycvvcgdkasgrhygavscEgcKgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs
interface signature	EKKR

Estimated binding specificities ?

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# IC=4.853 IC/col=0.971 n_of_columns=5

specificity:

A |   0   0   1   0  38
C |   0   0  19  96  19
G |  96  96   0   0  20
T |   0   0  76   0  19

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Dendrogram of similar interfaces ?

matrix format

  
  --DAKG--RGRG--   L       +-----------------------------4iqr_B    
                         +-2 
  ----KGVG--RG--   L   +-3 +-----------------------------5cbx_B    
                       ! ! 
  CAECKG--KGRG--   L --4 +-----------------------------6l6q_B    
                       ! 
  --EC----RGRGRT       !                            +8hbm_B    
                       +----------------------------1 
  CAECKG--KGRG--   L                                +7wnh_D

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updated Wed Dec 18 14:20:36 2024