7xv8_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN HOMODIMER BOUND TO DR1 RESPONSE ELEMENT
reference	Chen et al. 'Nucleic 51 1443 2023
source	Homo sapiens
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	7xv6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xv8_A interface=23,30,31, vveycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs > 7xv8_B interface=22,29,30, veycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs
interface signature	EKR/EKR

Estimated binding specificities ?

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# IC=7.138 IC/col=0.649 n_of_columns=11

specificity:

A |   5   4  66   4  24  24  24   0   0  54   0
C |   4   4  16  83  24  24  24   0   0  16  96
G |   4  83   4   4  24  24  24   0  96  12   0
T |  83   5  10   5  24  24  24  96   0  14   0

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updated Fri Aug 1 01:00:31 2025