7xv8_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN HOMODIMER BOUND TO DR1 RESPONSE ELEMENT
reference	Chen et al. 'Nucleic 51 1443 2023
source	Homo sapiens
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	7xv6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xv8_A interface=23,30,31, vveycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs > 7xv8_B interface=22,29,30, veycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs
interface signature	EKR/EKR

Estimated binding specificities ?

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# IC=1.516 IC/col=0.138 n_of_columns=11

specificity:

A |  17  15  38  15  24  24  24  12  15  34   8
C |  15  15  20  49  24  24  24  12  15  20  70
G |  15  49  19  17  24  24  24  12  51  22   8
T |  49  17  19  15  24  24  24  60  15  20  10

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updated Sat Jun 27 00:56:42 2026