7xv8_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN TR4 DNA-BINDING DOMAIN HOMODIMER BOUND TO DR1 RESPONSE ELEMENT
reference	Chen et al. 'Nucleic 51 1443 2023
source	Homo sapiens
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	7xv6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xv8_A interface=23,30,31, vveycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs > 7xv8_B interface=22,29,30, veycvvcgdkasgrhygavscEgckgffKRsvrknltyscrsnqdciinkhhrnrcqfcrlkkclemgmkmesvqs
interface signature	EKR/EKR

Estimated binding specificities ?

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# IC=7.165 IC/col=0.651 n_of_columns=11

specificity:

A |   0  16   4  96  24  24  24   4  12   0  84
C |   0  16  84   0  24  24  24   4   4  96   4
G |  96  12   4   0  24  24  24  84  16   0   4
T |   0  52   4   0  24  24  24   4  64   0   4

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updated Wed Jan 7 15:09:38 2026