interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE HUMAN FOXA2 BOUND TO THE TGTTTATT SITE (FORKHEAD MOTIF ATAAACA)
(Hepatocyte nuclear factor 3-beta)
referenceMacias et al. 'To ? ? 2022
sourceHomo sapiens
experimentX-ray (resolution=2.18, R-factor=0.225)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
reference complex7yze_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSF

Estimated binding specificities ?

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# IC=5.300 IC/col=0.883 n_of_columns=6 specificity:   
A |   9   9  11   0   0  96
C |  11   9   9   0   0   0
G |   9  67   9   0   0   0
T |  67  11  67  96  96   0
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updated Fri Sep 13 09:21:43 2024