interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO CD34 OFF-TARGET9 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.40, R-factor=0.214)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=2.843 IC/col=0.711 n_of_columns=4 specificity:   
A |  39   6   0  81
C |  19  78  96   4
G |  19   6   0   7
T |  19   6   0   4
scan!

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updated Sat Aug 2 22:39:04 2025