7zpp_ADIN : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF THE MVV CSC INTASOME AT 4.5A RESOLUTION
source	VISNA/MAEDI VIRUS EV1 KV1772
experiment	NMR
structural superfamily	Ribonuclease H-like;N-terminal Zn binding domain of HIV integrase;DNA-binding domain of retroviral integrase;
reference complex	7u32_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7zpp_A interface=29,33,49,230, ieniplaeeehnkwhqdavslhlefgipRtaaEdivqqcdvcqenkmpStlrgsnkrgidhwqvdythyedkiilvwvetnsgliyaervkgetgqefrvqtmkwyamfapkslqsdngpafvaestqllmkylgiehttgipwnpqsqalverthqtlkntleklipmfnafesalagtlitlnikrkgglgtspmdififnkeqqriqqqskskqekirfcyyrtrkRghpgewqgptqvlwggdgaivvkdrgtdrylviankdvkfipppk > 7zpp_D interface= idhwqvdythyedkiilvwvetnsgliyAervKgetgqefrvqtmkwyAmfapkslqsdngpafvaestqllmkylgiehttgipwnpqsqalverthqtlkntleklipmfnafesalagtlitlnikrkgglgtspmdififnkeqqriqqqskskqekirfcyyrtrkrghpgewqgptqvlwggdgaivvkdrgtdrylviankdvkfippp > 7zpp_I interface=147,150,154,157, ieniplaeeehnkwhqdavslhlefgiprtaaedivqqcdvcqenkmpstlrgsnkrgidhwqvdythyedkiilvwvetnsgliyaervkgetgqefrvqtmkwyamfapkslqsdngpafvaestqllmkylgiehttgipwnpQsqAlveRthQtlkntleklipmfnafesalagtlitlnikrkgglgtspmdififnkeqqriqqqskskqekirfcyyrtrkrghpgewqgptqvlwggdgaivvkdrgtdrylviankdvkfipppk > 7zpp_N interface= niplaeeehnkwhqdavslhlefgiprtaaedivqqcdvcqenkkrgidhwqvdythyedkiilvwvetnsgliyaervkgetgqefrvqtmkwyamfapkslqsdngpafvaestqllmkylgiehttgipwnpqsqalverthqTlkNtleKliPmfnafesalagtlitlnikrkgglgtspmdififnkeqqriqqqskskqekirfcyyrtrkrghpgewqgptqvlwggdgaivvkdrgtdrylviankdvkfipppk
interface signature	RESR/AKA/QARQ/TNKP

Estimated binding specificities ?

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# IC=6.368 IC/col=0.425 n_of_columns=15

specificity:

A |   9   9  24  24  24  24  24  24  24  24   0   9   0   0   0
C |  73   7  24  24  24  24  24  24  24  24  81   7  96   0  96
G |   7  66  24  24  24  24  24  24  24  24   8   7   0  96   0
T |   7  14  24  24  24  24  24  24  24  24   7  73   0   0   0

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updated Wed Sep 11 19:52:22 2024