7u32_A : 3D-footprint complex

structure name	MVV CLEAVED SYNAPTIC COMPLEX (CSC) INTASOME AT 3.4 A RESOLUTION (INTEGRASE)
source	VISNA/MAEDI VIRUS EV1 KV1772
experiment	NMR
structural superfamily	Ribonuclease H-like;N-terminal Zn binding domain of HIV integrase;DNA-binding domain of retroviral integrase;
sequence family	Integrase core domain; Integrase DNA binding domain; Integrase Zinc binding domain;
multimeric complexes	5m0r_AI 5m0r_DN 5m0r_FL 7u32_AFL 7u32_DIN 7z1z_DEIN 7z1z_FL 7zpp_ADIN 7zpp_FL
redundant complexes	5m0r_N 7z1z_M 7zpp_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7u32_A interface=148,151,154,155,158, wieniplaeeehnkwhqdavslhlefgiprtaaedivqqcdvcqenkmpstlrgsnkrgidhwqvdythyedkiilvwvetnsgliyaervkgetgqefrvqtmkwyamfapkslqsdngpafvaestqllmkylgiehttgipwnpQsqAlvERthQtlkntleklipmfnafesalagtlitlnikrkgglgtspmdififnkeqqriqqqskskqekirfcyyrtrkrghpgewqgptqvlwggdgaivvkdrgtdrylviankdvkfipppk
interface signature	QAERQ

Estimated binding specificities ?

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# IC=3.320 IC/col=0.830 n_of_columns=4

specificity:

A |  19   2   5   0
C |  16  88   3  96
G |  16   4  85   0
T |  45   2   3   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  HG--DT----------------QGECSGHCQT----------           +-----------------------------6rwm_A    
                                                     +-2 
  ------KT--------HTETPAQAEARC--------------   L     ! !            +----------------3oym_A    
                                                   +-3 +------------1 
  HGQTDT--TAHA----------QGECSCKG------------       ! !              +----------------6vdk_A    
                                                 --4 ! 
  --------------------------------RAYACAPAWA       ! +-----------------------------3jca_H    
                                                   ! 
  ------------KTYC--------------------------   L   +-----------------------------6x68_D

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updated Wed Dec 18 11:28:50 2024