8ap1_AB : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF YEAST MITOCHONDRIAL RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH TWO GTP MOLECULES POISED FOR DE NOVO INITIATION (IC2)
experiment	NMR
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6ymv_A 6ymv_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ap1_A interface=142,145,173,219,220,221,223,224,278,406,594,598,601,603,606,610,611,706,708,717,718,730,738,742, inffeiynslptleekkafesalnifnqdrqkvlenrateaarerwkhdfeeakarknlnvklwkwynemlplvkeeinhcrsllseklsdkkglnkvdtnrlgygpyltlidpgkmcvitilellklnstggviegmrtaRavIsvgkaiemefrseqvlksesqakilwpQsirarigsvlismliqvakvsvqgvdpvtkakvhgeapafahgyqYHNgSKlgvlkihktlirqlngerliasvqpqllpmlvepkpwvnwrsggyhytqstllRtkdspeqvaylkaasdngdidrvydglnvlgrtpwtvnrkvfdvvsqvwnkgegfldipgaqdemvlppappknsdpsilrawklqvktiankfssdrsnrcdtnykleiaraflgeklyfphnldfRgrayplsphfnhlgndmsrgllifwhgkklgpsglkwlkihlsnlfgfdklplkdrvafteshlqdikdsaenpltgdrwwttadkpwqalatcfelnevmkmdnpeefishqpvhqdgtcnglqhyaalggdvegatqvnlvpsdkpqdvyahvarlvqkrleiaaekgdenakilkdkitrkvvkQtvmTnvYgVtyVgatFQiakqlspifddrkesldfskyltkhvfsairelfhsahliqdwlgesakrisksirldvdeksfkngnkpdfmssviwttplglpivqpyreesKkQvetnlqtvFIsdpfavnpvnaRrqkaglpPnfiHsldashmllsaaecgkqgldfasvhdsywthasdidtmnvvlreqfiklhevdlvlrlkeefdqryknyvkigklkrstdlaqkiirirkdlsrklgrsttladeiyfekkrqellnspliedrnvgekmvttvslfeditdldamsvllplrlpeippkgdfdvtvlrnsqyffs > 8ap1_B interface=15,102,104,143,145,147,148,334,335, svpipgikdisklkFfygfkylwnptvynkifdkldltktykhpeelkvldlypgvgiqsaifynkycprqysllekrsslykflnakfegsplqilkrdpYdWstysnlideerifvpevqssdhindkfltvanvtgegsEgLiMQwlscignknwlyrfgkvkmllwmpsttarkllarpgmhsrskcsvvreaftdtkliaisdanelkgfdsqcieewdpilfsaaeiwptkgkpialvemdpidfdfdvdnwdyvtrhlmilkrtplntvmdslghggqqyfnsritdkdllkkcpidltndefiyltklfmewpfkpdilmdfvdmYQtehs
interface signature	RIQYHNSKRRQTYVVFQKQFIRPH/FYWELMQYQ

Estimated binding specificities ?

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# IC=10.630 IC/col=1.063 n_of_columns=10

specificity:

A |  67   0   0   9  96   0  96  96   0  67
C |   9  96  96  11   0  96   0   0   0   9
G |  11   0   0  67   0   0   0   0   0  11
T |   9   0   0   9   0   0   0   0  96   9

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updated Fri Aug 1 04:14:54 2025