8c5s_AB : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF YEAST MITOCHONDRIAL RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH 7-MER RNA, PPPGPGPUPAPAPAPU (IC7)
experiment	NMR
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6ymv_A 6ymv_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c5s_A interface=141,220,222,224,225,360,364,370,371,374,377,407,411,595,599,602,604,605,606,607,612,709,716,718,731,739,743, inffeiynslptleekkafesalnifnqdrqkvlenrateaarerwkhdfeeakargdisieknlnvklwkwynemlplvkeeinhcrsllseklsdkkglnkvdtnrlgygpyltlidpgkmcvitilellklnstggvIegmrtaravisvgkaiemefrseqvlkkilwpqsirarigsvlismliqvakvsvqgvdpvtkakvhgeapafahgyqYhNgSKlgvlkihktlirqlngerliasvqpqllpmlvepkpwvnwrsggyhytqstllrtkdspeqvaylkaasdngdidrvydglnvlgrtpwtvnrkvfdvvsqvwnkgegfldipgaqdemvlppappknsdpsilRawkLqvktiANkfSsdRsnrcdtnykleiaraflgeklyfphnldfRgraYplsphfnhlgndmsrgllifwhgkklgpsglkwlkihlsnlfgfdklplkdrvafteshlqdikdsaenpltgdrwwttadkpwqalatcfelnevmkmdnpeefishqpvhqdgtcnglqhyaalggdvegatqvnlvpsdkpqdvyahvarlvqkrleiaaekgdenakilkdkitrkvvkQtvmTnvYgVTYVgatfQiakqlspifddrkesldfskyltkhvfsairelfhsahliqdwlgesakrisksirldvdeksfkngnkpdfmssviwttplglpivqpyreeskkQvetnlqTvFisdpfavnpvnaRrqkaglpPnfiHsldashmllsaaecgkqgldfasvhdsywthasdidtmnvvlreqfiklhevdlvlrlkeefdqryknyvkigklkrstdlaqkiirirkdlsrklgrsttladeiyfekkrqellnspliedrnvgekmvttvslfeditdldalelsgmsvllplrlpeippkgdfdvtvlrnsqyffs > 8c5s_B interface=17,100,102,103,104,143,145,147,148,335, svpipgikdisklkffYgfkylwnptvynkifdkldltktykhpeelkvldlypgvgiqsaifynkycprqysllekrsslykflnakfegsplqilkrDpYDWstysnlideerifvpevqssdhindkfltvanvtgegsEgLiMQwlscignknwlyrfgkvkmllwmpsttarkllarpgmhsrskcsvvreaftdtkliaisdanelkgfdsqcieewdpilfsaaeiwptkgkpialvemdpidfdfdvdnwdyvtrhlmilkrtplntvmdslghggqqyfnsritdkdllkkcpidltndefiyltklfmewpfkpdilmdfvdmyQt
interface signature	IYNSKRLANSRRYQTYVTYVQQTFRPH/YDYDWELMQQ

Estimated binding specificities ?

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# IC=10.659 IC/col=0.711 n_of_columns=15

specificity:

A |  13  96   0  63  70   0   0  96  24  21  24  34  52   0   0
C |  13   0   0  13   8   0   0   0  24  23  24  20  14   0   0
G |  14   0   0  10   8  96   0   0  24  21  24  20  16   0  96
T |  56   0  96  10  10   0  96   0  24  31  24  22  14  96   0

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updated Wed Jan 7 20:06:16 2026