8c5u_AB : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF YEAST MITOCHONDRIAL RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH 8-MER RNA, PPPGPGPUPAPAPAPUPG (IC8)
experiment	NMR
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6ymv_A 6ymv_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c5u_A interface=135,142,144,148,171,217,219,221,222,375,379,404,408,599,601,602,603,604,706,715,716,717,728,740, inffeiynslptleekkafesalnifnqdrqkvlenrateaarerwkhdfeeakargdisieknlnvklwkwynemlplvkeeinhcrsllseklsdkkglnkvdtnrlgygpyltlidpgkmcvitilellklNstgegmRtAravIsvgkaiemefrseqvlkkilwpQsirarigsvlismliqvakvsvqgvdpvtkakvhgeapafahgyqYhNgSKlgvlkihktlirqlngerliasvqpqllpmlvepkpwvnwrsggyhytqstllrtkdspeqvaylkaasdngdidrvydglnvlgrtpwtvnrkvfdvvsqvwnkgegfldipgaqdemvlppappknsdpsilrawklqvktiankfssdrSnrcDtnykleiaraflgeklyfphnldfRgraYplsphfnhlgndmsrgllifwhgkklgpsglkwlkihlsnlfgfdklplkdrvafteshlqdikdsaenpltgdrwwttadkpwqalatcfelnevmkmdnpeefishqpvhqdgtcnglqhyaalggdvegatqvnlvpsdkpqdvyahvarlvqkrleiaaekgdenakilkdkitrkvvkqtvmtnvYgVTYVgatfqiakqlspifddrkesldfskyltkhvfsairelfhsahliqdwlgesakrisksirldvdeksfkngnkpdfmssviwttplglpivqpyreeskkQvetnlqtvFISdpfavnpvnaRrqkaglppnfiHsldashmllsaaecgkqgldfasvhdsywthasdidtmnvvlreqfiklhevdlvlrlkeefdqryknyvkigklkrstdlaqkiirirkdlsrklgrsttladeiyfekkrqellnspliedrnvgekmvttvslfeditdldalegmsvllplrlpeippkgdfdvtvlrnsqyffs > 8c5u_B interface=17,77,100,102,103,104,142,143,145,147,148, svpipgikdisklkffYgfkylwnptvynkifdkldltktykhpeelkvldlypgvgiqsaifynkycprqyslleKrsslykflnakfegsplqilkrDpYDWstysnlideerifvpevqssdhindkfltvanvtgegSEgLiMQwlscignknwlyrfgkvkmllwmpsttarkllarpgmhsrskcsvvreaftdtkliaisdanelkgfdsqcieewdpilfsaaeiwptkgkpialvemdpidfdfdvdnwdyvtrhlmilkrtplntvmdslghggqqyfnsritdkdllkkcpidltndefiyltklfmewpfkpdilmd
interface signature	NRAIQYNSKSDRYYVTYVQFISRH/YKDYDWSELMQ

Estimated binding specificities ?

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# IC=12.470 IC/col=0.734 n_of_columns=17

specificity:

A |   0  96   0  96  96   0  24  96  24  16  24  24  24  24   0   0  57
C |   0   0   0   0   0   0  24   0  24  13  24  24  24  24   0  96  13
G |   0   0   0   0   0  96  24   0  24  13  24  24  24  24  96   0  13
T |  96   0  96   0   0   0  24   0  24  54  24  24  24  24   0   0  13

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updated Wed Jan 7 20:07:07 2026