8c7s_AB : 3D-footprint complex

structure name	TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH ILE, GTP, AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES
reference	Sauer-Eriksson et al. 'Nucleic 51 7631 2023
source	Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300)
experiment	X-ray (resolution=3.05, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	8c7s_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c7s_A interface=214,215,218,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgitRSviVnalrklesagviesrslgMkgtfikvkkekfldeleks > 8c7s_B interface=213,215,216,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgiTrSVivnalrklesagviesrslgMkgtfikvkkekfldeleks
interface signature	RSVM/TSVM

Estimated binding specificities ?

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# IC=7.288 IC/col=0.455 n_of_columns=16

specificity:

A |  57  87  24  24   3   0   6   3   0  24  24  24  24  24   9  60
C |   9   3  24  24   3   0  78   3   0  24  24  24  24  24  12  15
G |  12   3  24  24   3   0   6   3  96  24  24  24  24  24   6   6
T |  18   3  24  24  87  96   6  87   0  24  24  24  24  24  69  15

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updated Wed Jan 7 20:08:03 2026