8c7s_AB : 3D-footprint complex

structure name	TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH ILE, GTP, AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES
reference	Sauer-Eriksson et al. 'Nucleic 51 7631 2023
source	Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300)
experiment	X-ray (resolution=3.05, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	8c7s_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c7s_A interface=214,215,218,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgitRSviVnalrklesagviesrslgMkgtfikvkkekfldeleks > 8c7s_B interface=213,215,216,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgiTrSVivnalrklesagviesrslgMkgtfikvkkekfldeleks
interface signature	RSVM/TSVM

Estimated binding specificities ?

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# IC=8.426 IC/col=0.527 n_of_columns=16

specificity:

A |  59  93  24  24   0   0   3   0   0  24  24  24  24  24  19  53
C |  19   3  24  24   0   0  88   3   0  24  24  24  24  24   7   7
G |  11   0  24  24   0   0   5   0  96  24  24  24  24  24   5  21
T |   7   0  24  24  96  96   0  93   0  24  24  24  24  24  65  15

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updated Fri Aug 1 05:28:59 2025