8c7s_AB : 3D-footprint complex

structure name	TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH ILE, GTP, AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES
reference	Sauer-Eriksson et al. 'Nucleic 51 7631 2023
source	Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300) / Staphylococcus aureus (strain USA300)
experiment	X-ray (resolution=3.05, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	8c7s_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c7s_A interface=214,215,218,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgitRSviVnalrklesagviesrslgMkgtfikvkkekfldeleks > 8c7s_B interface=213,215,216,237, msllsktrelntllqkhkgiavdfkdvaqtissvtvtnvfivsrrgkilgsslnellksqriiqmleerhipseyterlmevkqtesnididnvltvfppenrelfidsrttifpilgggerlgtlvlgrvhddfnendlvlgeyaatvigmeilrekhsevekeardkaaitmainslsysekeaiehifeelggteglliaskvadrvgiTrSVivnalrklesagviesrslgMkgtfikvkkekfldeleks
interface signature	RSVM/TSVM

Estimated binding specificities ?

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# IC=7.874 IC/col=0.492 n_of_columns=16

specificity:

A |  68  86  24  24   3   0   3   4   0  24  24  24  24  24  10  61
C |   6   3  24  24   4   0  86   3   0  24  24  24  24  24   0   9
G |  13   4  24  24   3   0   3   0  96  24  24  24  24  24  15  11
T |   9   3  24  24  86  96   4  89   0  24  24  24  24  24  71  15

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updated Sun Dec 15 22:53:55 2024