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legend  pdf

structure nameTRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM ENTEROCOCCUS FAECALIS IN COMPLEX WITH LEU AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES
(GTP-sensing transcriptional pleiotropic repressor CodY)
referenceSauer-Eriksson et al. 'Nucleic 51 7631 2023
sourceEnterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583)
experimentX-ray (resolution=3.15, R-factor=0.250)
structural superfamily"Winged helix" DNA-binding domain;GAF domain-like;
sequence familyCodY GAFlike domain; CodY helixturnhelix domain;
multimeric complexes8c7u_ABCD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSTRSVVM

Estimated binding specificities ?

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# IC=7.307 IC/col=0.812 n_of_columns=9 specificity:   
A |   0   0  85  80  75  24  16  10   5
C |   0   0   0   6  10  24  10   0  91
G |   0  96   6   5   5  24   5   6   0
T |  96   0   5   5   6  24  65  80   0
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Wed Dec 18 16:26:33 2024