8c7u_A : 3D-footprint complex

structure name	TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM ENTEROCOCCUS FAECALIS IN COMPLEX WITH LEU AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES (GTP-sensing transcriptional pleiotropic repressor CodY)
reference	Sauer-Eriksson et al. 'Nucleic 51 7631 2023
source	Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583)
experiment	X-ray (resolution=3.15, R-factor=0.250)
structural superfamily	"Winged helix" DNA-binding domain;GAF domain-like;
sequence family	CodY GAFlike domain; CodY helixturnhelix domain;
multimeric complexes	8c7u_ABCD
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c7u_A interface=210,219,220,221,222,224,243, amatllektrqvnellqknnlfdvqaelpynkmamilgdilesnayiisssgdllgytekldvnnariknmfkekkfpqgyteavdmlkvteanipidsdltafpfesrelypfglttivplygagkrlgtiilarveksfneddlvlaeysatvvgmqilyhqsrtieaevrsatavqmaintlsyselkavhaifealdgeegrltaSsiadeigiTRSViVnalrklesagiiesrslgMkgtylkvlnqqfikelek
interface signature	STRSVVM

Estimated binding specificities ?

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# IC=1.178 IC/col=0.041 n_of_columns=29

specificity:

A |  24  24  24  24  24  24  24  24  24  24  24  18  39  34  24  19  19  16  14  74  24  24  24  24  24  24  24  24  24
C |  24  24  24  24  24  24  24  24  24  24  24  18  19  20  24  19  20  19  54   7  24  24  24  24  24  24  24  24  24
G |  24  24  24  24  24  24  24  24  24  24  24  42  19  20  24  20  19  16  14   7  24  24  24  24  24  24  24  24  24
T |  24  24  24  24  24  24  24  24  24  24  24  18  19  22  24  38  38  45  14   8  24  24  24  24  24  24  24  24  24

scan!

Dendrogram of similar interfaces ?

matrix format

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updated Wed Dec 20 01:50:08 2023