8c7u_ABCD : 3D-footprint complex

structure name	TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY FROM ENTEROCOCCUS FAECALIS IN COMPLEX WITH LEU AND A 30-BP DNA FRAGMENT ENCOMPASSING TWO OVERLAPPING BINDING SITES
reference	Sauer-Eriksson et al. 'Nucleic 51 7631 2023
source	Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583) / Enterococcus faecalis (strain ATCC 700802 / V583)
experiment	X-ray (resolution=3.15, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;GAF domain-like;
reference complex	8c7u_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8c7u_A interface=210,219,220,221,222,224,243, amatllektrqvnellqknnlfdvqaelpynkmamilgdilesnayiisssgdllgytekldvnnariknmfkekkfpqgyteavdmlkvteanipidsdltafpfesrelypfglttivplygagkrlgtiilarveksfneddlvlaeysatvvgmqilyhqsrtieaevrsatavqmaintlsyselkavhaifealdgeegrltaSsiadeigiTRSViVnalrklesagiiesrslgMkgtylkvlnqqfikelek > 8c7u_B interface=219,220,221,224,243, amatllektrqvnellqknnlfdvqaelpynkmamilgdilesnayiisssgdllgytekldvnnariknmfkekkfpqgyteavdmlkvteanipidsdltafpfesrelypfglttivplygagkrlgtiilarveksfneddlvlaeysatvvgmqilyhqsrtieaevrsatavqmaintlsyselkavhaifealdgeegrltassiadeigiTRSviVnalrklesagiiesrslgMkgtylkvlnqqfikelek > 8c7u_C interface=212,213,214,215,217,236, matllektrqvnellqkqaelpynkmamilgdilesnayiisssgdllgytekldvnnariknmfkekkfpqgyteavdmlkvteanipidsdltafpfesrelypfglttivplygagkrlgtiilarveksfneddlvlaeysatvvgmqilyhqsrtieaevrsatavqmaintlsyselkavhaifealdgeegrltassiadeigiTRSViVnalrklesagiiesrslgMkgtylkvlnqqfikelek > 8c7u_D interface=220,221,222,225,244, gamatllektrqvnellqknnlfdvqaelpynkmamilgdilesnayiisssgdllgytekldvnnariknmfkekkfpqgyteavdmlkvteanipidsdltafpfesrelypfglttivplygagkrlgtiilarveksfneddlvlaeysatvvgmqilyhqsrtieaevrsatavqmaintlsyselkavhaifealdgeegrltassiadeigiTRSviVnalrklesagiiesrslgMkgtylkvlnqqfikelek
interface signature	STRSVVM/TRSVM/TRSVVM/TRSVM

Estimated binding specificities ?

readout + contact

# IC=17.553 IC/col=0.702 n_of_columns=25

specificity:

A |  75  24  24  24   0  24   5  96   0  90  96  24   7   0   5   0  96   0  68  96  24  24  24   2   7
C |  12  24  24  24   0  24  85   0   0   2   0  24  17   0   5  93   0   0  10   0  24  24  24   6   7
G |   2  24  24  24   0  24   5   0  96   0   0  24  12   0   8   3   0  96  11   0  24  24  24   5   2
T |   7  24  24  24  96  24   1   0   0   4   0  24  60  96  78   0   0   0   7   0  24  24  24  83  80

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updated Wed Jan 7 20:08:16 2026