8cef_GHK : 3D-footprint complex

structure name	ASYMMETRIC DIMERIZATION IN A TRANSCRIPTION FACTOR SUPERFAMILY IS PROMOTED BY ALLOSTERIC INTERACTIONS WITH DNA
reference	Billas et al. 'Nucleic 51 8864 2023
source	Mus musculus
experiment	X-ray (resolution=2.49, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	8cef_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8cef_G interface=22,25,26,29,30,80, krlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvR > 8cef_H interface=23,26,27,30,31,81,84, pkrlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvRggRqky > 8cef_K interface=24,27,28,31,32,82,85, lpkrlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvRggRqky
interface signature	EKAKRR/EKAKRRR/EKAKRRR

Estimated binding specificities ?

readout + contact

# IC=18.290 IC/col=1.016 n_of_columns=18

specificity:

A |   3   8  24  85   0   0  10   0  96   0   0  10   4   0  92   0   0  10
C |   5  75  24   3   0   0   8  96   0  96  96   8   0   0   0  96  96  10
G |   3   3  24   3  96  96   6   0   0   0   0  68   0  96   4   0   0   4
T |  85  10  24   5   0   0  72   0   0   0   0  10  92   0   0   0   0  72

scan!

home
updated Sun Dec 15 22:55:35 2024