8cef_GHK : 3D-footprint complex

structure name	ASYMMETRIC DIMERIZATION IN A TRANSCRIPTION FACTOR SUPERFAMILY IS PROMOTED BY ALLOSTERIC INTERACTIONS WITH DNA
reference	Billas et al. 'Nucleic 51 8864 2023
source	Mus musculus
experiment	X-ray (resolution=2.49, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	8cef_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8cef_G interface=22,25,26,29,30,80, krlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvR > 8cef_H interface=23,26,27,30,31,81,84, pkrlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvRggRqky > 8cef_K interface=24,27,28,31,32,82,85, lpkrlclvcgdvasgyhygvascEacKAffKRtiqgsieyscpasneceitkrrrkacqacrftkclrvgmlkegvrldrvRggRqky
interface signature	EKAKRR/EKAKRRR/EKAKRRR

Estimated binding specificities ?

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# IC=18.596 IC/col=1.033 n_of_columns=18

specificity:

A |   6   7  24  87   0   0  11   0  96   0   0  11   0   0  96   0   0   3
C |   3  70  24   3   0   0   7  96   0  96  96   7   0   0   0  96  96  13
G |   3   7  24   3  96  96   8   0   0   0   0  66   0  96   0   0   0   3
T |  84  12  24   3   0   0  70   0   0   0   0  12  96   0   0   0   0  77

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updated Fri Aug 1 05:30:28 2025