8cxv_AB : 3D-footprint complex

structure name	CAMA ADENINE METHYLTRANSFERASE COMPLEXED TO COGNATE SUBSTRATE DNA AND COMPOUND 3
reference	Horton et al. J.Med.Chem. 66 934 2023
source	Clostridioides difficile 630
experiment	X-ray (resolution=2.26, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	8cxy_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8cxv_A interface=3,133,136,139,140,160,161,189,221,223,224,226,314,317,347,393,394,399,406,407,409,423,424,440,441,442,444,481,482,485,489, giYytpkiivdyivkktlknhdiiknpyprildiscgcgnfllevydilydlfeeniyelkkkydenywtvdnihrhilnyciygadidekaisilkdsltnkkdesdikinlfccdslkkkwrykfdyivgNppYigHKklekkykkfllekysevykDKadlyfcfykkiidilkqggigsvitprYfleslsgkdlreyiksnvnvqeivdflganiFkNIgVssciltfdkkktketyidvfkiknedicinkfetleellksskfehfninqrllsdewilvnkddetfynkiqekckyslediaisfQgiItgcdkafilskddvklnlvddkflkcwikSkninkyivdkseyrliysndidnentnkrildeiiglyktklenrREcksgIrkwyelQWgReklfferkkimypYKsnenrfaidydnnfsSADvYsffikeeyldkfsyeylvgilnssvydkyfkitakkMSknIydyYpnkvmkirifrdnnyeeienlskqiisillnksidkgkveklqikmdnlimdslgi > 8cxv_B interface=404, giyytpkiivdyivkktlknhdiiknpyprildiscgcgnfllevydilydlfeeniyelkkkydenywtvdnihrhilnyciygadidekaisilkdsltnkkvvndldesdikinlfccdslkkkwrykfdyivgnppyighkklekkykkfllekysevykdkadlyfcfykkiidilkqggigsvitpryfleslsgkdlreyiksnvnvqeivdflganifknigvssciltfdkkktketyidvfkiknedicinkfetleellksskfehfninqrllsdewilvnkddetfynkiqekckyslediaisfqgiitgcdkafilskddvklnlvddkflkcwikskninkyivdkseyrliysndidnentnkrildeiiglyktklenrrecksgIrkwyelqwgreklfferkkimypyksnenrfaidydnnfssadvysffikeeyldkfsyeylvgilnssvydkyfkitakkmskniydyypnkvmkirifrdnnyeeienlskqiisillnksidkgkveklqikmdnlimdslgi
interface signature	YNYHKDKYFNIVQISREIQWRYKSADYMSIY/I

Estimated binding specificities ?

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# IC=9.127 IC/col=1.141 n_of_columns=8

specificity:

A |   3   0  96  96  96  96  96  13
C |   3  96   0   0   0   0   0  14
G |   5   0   0   0   0   0   0  56
T |  85   0   0   0   0   0   0  13

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updated Sat Jun 27 06:00:15 2026