interface graph thumbnail
legend  pdf

structure nameHUMAN CST-DNA POLYMERASE ALPHA/PRIMASE PREINITIATION COMPLEX BOUND TO 4XTEL-FOLDBACK TEMPLATE
(CST COMPLEX SUBUNIT CTC1)
sourceHOMO SAPIENS
experimentNMR
multimeric complexes8d0b_ABF 8d0k_ABCDEF
redundant complexes8d0k
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRCYERSNYCRFRLEVQPKKRQFRR

Estimated binding specificities ?

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# IC=9.328 IC/col=0.848 n_of_columns=11 specificity:   
A |   0  96   0  24  24  24  24  96   0   0   0
C |   0   0   0  24  24  24  24   0   0   0   0
G |   0   0  96  24  24  24  24   0  96  96  96
T |  96   0   0  24  24  24  24   0   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------------------------------------------------------------------------------------------------------------------------RT----------------------------------                     +-----------------------------4l5r_C    
                                                                                                                                                                                         ! 
  ------------------------------------------------RTFTNT--RT----------------------------------------------TT------------------KT----FT----STFTST--------------------   L               +-6      +----------------------4gnx_Z    
                                                                                                                                                                                       ! ! +----2 
  --------------------------------------------------------------------TTKT----------TTATNTTTFTAT--FT--NT------------------------------------------------------------   L               ! ! !    +----------------------6bhx_B    
                                                                                                                                                                                       ! +-5 
  ------------------------------------------------------------------------STTTDT--------------------QC--HC--FA--KT------------TG--RA--YCQCLGKGDGQG------------------   L               !   !                    +------1qzh_E    
                                                                                                                                                                                     +-7   !  +-----------------1 
  KGFGSTTTDTTGTGLAFAQGQGIA------------------------------------------------------------------------------------------------------------------------------------------   L             ! !   +--4                 +------3kjp_A    
                                                                                                                                                                                     ! !      ! 
  --------------------------------------------------------------RT--KT--------------AT--------TT--WT--RT----------RT--IT--YT--------------------NTNTMTQTLT----------   L           +-8 !      +------------------------6irq_A    
                                                                                                                                                                                   ! ! ! 
  --------------------------------------------------------------------------------------------------------------------------------------------------------MGRGMGFGDG               ! ! +-----------------------------7lma_D    
                                                                                                                                                                                 +-9 ! 
  ----------------------------------------------------------EG------YG------------------------------------------------------EG--------------NG--HG------------------             ! ! +-----------------------------3u58_C    
                                                                                                                                                                                 ! ! 
  ------------------------------------------------------------KG----------------------------------------------------------------------------------------------------   L      +-10 +-----------------------------4jbm_A    
                                                                                                                                                                              !  !  
  ------------------------------------------------------RC----------------------------------------------------------------------------------------------------------          !  !     +-----------------------5z7d_C    
                                                                                                                                                                           +-11  +-----3 
  KGFGSTTTDTTGTGLAFTQGQGIA------------------------------------------------------------------------------------------------------------------------------------------   L   !  !        +-----------------------7qxs_P    
                                                                                                                                                                         -12  !  
  ----------------------------------------------------------------VC------RC----VCNC----------TCECWC--RC------FC--KCECVCECYC----------------NCVC--TC--QC------------   L   !  +-----------------------------1eyg_D    
                                                                                                                                                                           !  
  ------------------------RTIGWGDGKGDTHTLTYAEGIGHG------------------------------------------------------------------------------------------------------------------   L   +-----------------------------4hja_A    
                                                                                                                                                                         

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updated Wed Dec 18 16:46:48 2024