8d86_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE CO- CRYSTALLIZED WITH A GUEST SMALL MOLECULE, NETROPSIN. (Replication initiation protein)
reference	Orun et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.12, R-factor=0.197)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8d86_C interface=56,57,58,60,61,64,94,164,165,167,169,170,173,174,200, nsprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdits
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.139 IC/col=0.673 n_of_columns=21

specificity:

A |   0   7  24  24   0   0   3  24  24  24  24   3   0   0   0  96   0  67  24   3   3
C |   3  11  24  24   0   0  81  24  24  24  24   3   0   0  96   0  96   7  24  10  10
G |   0  71  24  24  92  96   3  24  24  24  24   5  96   0   0   0   0  10  24  67   7
T |  93   7  24  24   4   0   9  24  24  24  24  85   0  96   0   0   0  12  24  16  76

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updated Fri Sep 13 10:17:24 2024