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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE CO- CRYSTALLIZED WITH A GUEST SMALL MOLECULE, NETROPSIN.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.12, R-factor=0.197)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.240 IC/col=0.678 n_of_columns=21 specificity:   
A |   0  10  24  24   0   0   3  24  24  24  24   3   0   0   0  96   0  67  24   7   4
C |   4  10  24  24   1   0  80  24  24  24  24   1   0   0  96   0  96   8  24  10   7
G |   0  69  24  24  92  96   3  24  24  24  24   0  96   0   0   0   0   7  24  64   7
T |  92   7  24  24   3   0  10  24  24  24  24  92   0  96   0   0   0  14  24  15  78
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updated Tue Dec 17 16:04:18 2024