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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE GROWN IN A CALCIUM CHLORIDE CRYSTALLIZATION SOLUTION.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.10, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.927 IC/col=0.663 n_of_columns=21 specificity:   
A |  81   8  24  10   0   0   0  96   0  87  24  24  24  24  24   0   2  24  12   8  93
C |   2  70  24  10   0   0   0   0  96   2  24  24  24  24  24  96  93  24  13  70   0
G |   8   8  24   8  96   0  96   0   0   5  24  24  24  24  24   0   0  24   8   8   2
T |   5  10  24  68   0  96   0   0   0   2  24  24  24  24  24   0   1  24  63  10   1
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updated Fri Jan 9 21:18:31 2026