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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE GROWN IN A CALCIUM CHLORIDE CRYSTALLIZATION SOLUTION.
(Replication initiation protein)
referenceOrun et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.10, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.113 IC/col=0.672 n_of_columns=21 specificity:   
A |   1   9  60  24   0   0  24  24  24  24  24   3   0   0   0  96   0  78  24   8   6
C |   3   9  15  24   0   0  24  24  24  24  24   3   0   0  96   0  96   6  24   6   6
G |   0  69   9  24  92  96  24  24  24  24  24   3  96   0   0   0   0   6  24  76   4
T |  92   9  12  24   4   0  24  24  24  24  24  87   0  96   0   0   0   6  24   6  80
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updated Sat Aug 2 23:24:46 2025