8d8m_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE GROWN IN A CALCIUM CHLORIDE CRYSTALLIZATION SOLUTION. (Replication initiation protein)
reference	Orun et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.10, R-factor=0.227)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8d8m_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.880 IC/col=0.661 n_of_columns=21

specificity:

A |  80   7  24  12   0   0   0  96   0  90  24  24  24  24  24   0   2  24  15   7  93
C |   4  64  24   7   0   0   0   0  96   2  24  24  24  24  24  96  93  24  10  70   0
G |   7   7  24   7  96   0  96   0   0   2  24  24  24  24  24   0   1  24  12   9   2
T |   5  18  24  70   0  96   0   0   0   2  24  24  24  24  24   0   0  24  59  10   1

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updated Mon Jun 29 06:39:51 2026