interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE THETA IN COMPLEX WITH ALLOSTERIC INHIBITOR
referencePau et al.
experimentX-ray (resolution=2.59, R-factor=0.248)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
reference complex8e24_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKKRNNQYMNQ

Estimated binding specificities ?

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# IC=4.007 IC/col=0.668 n_of_columns=6 specificity:   
A |   9  24  69   0   9   0
C |  11  24   9   0  11   0
G |   9  24   9   0   9  96
T |  67  24   9  96  67   0
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updated Fri Jan 9 21:32:26 2026