interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE THETA IN COMPLEX WITH ALLOSTERIC INHIBITOR
(DNA polymerase theta)
referencePau et al.
sourceHomo sapiens
experimentX-ray (resolution=2.34, R-factor=0.233)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
redundant complexes8e23_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRNNQYYMNQH

Estimated binding specificities ?

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# IC=2.674 IC/col=0.669 n_of_columns=4 specificity:   
A |  69   9   9   0
C |   9  11  11   0
G |   9   9   9  96
T |   9  67  67   0
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updated Sat Jan 10 23:07:35 2026