interface graph thumbnail
legend  pdf

structure nameT. CRUZI TOPOISOMERASE II ALPHA BOUND TO DSDNA AND THE COVALENT INHIBITOR CT1
experimentNMR
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
multimeric complexes8gcc_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKRIA

Estimated binding specificities ?

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# IC=5.339 IC/col=0.763 n_of_columns=7 specificity:   
A |  11   0  24  67   9   0   0
C |  67   0  24   9   9   0   0
G |   9   0  24   9   9   0  96
T |   9  96  24  11  69  96   0
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updated Tue Jun 30 15:24:30 2026