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structure nameLOOP DELETED DNA POLYMERASE THETA POLYMERASE DOMAIN IN COMPLEX WITH DOUBLE STRAND DNA OVERHANG AND INHIBITOR
(DNA polymerase theta)
referenceFried et al. 'Nat 15 2862 2024
sourceHomo sapiens
experimentX-ray (resolution=3.24, R-factor=0.230)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
redundant complexes6xbu_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNKRNQYMNQH

Estimated binding specificities ?

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# IC=4.853 IC/col=0.971 n_of_columns=5 specificity:   
A |   0  19   0   0  19
C |   0  76   0  96  19
G |  96   0  96   0  20
T |   0   1   0   0  38
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updated Sat Sep 14 10:09:23 2024