8hml_AB : 3D-footprint complex

structure name	CO-CRYSTAL STRUCTURE OF THE C TERMINAL DNA BINDING DOMAIN OF SACCHAROPOLYSPORA ERYTHRAEA GLNR IN COMPLEX WITH ITS CONSERVED PROMOTER DNA IN 2.95 ANGSTROM RESOLUTION
reference	Xu et al. Proc.Natl.Acad.Sci.USA 120 e2300282120 2023
source	Saccharopolyspora erythraea NRRL 2338
experiment	X-ray (resolution=2.95, R-factor=?)
structural superfamily	C-terminal effector domain of the bipartite response regulators;
reference complex	8hig_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8hml_A interface=63,64,66,67,70,71, magmltvgdlvieestytarlkgraleltykefellkylaqhagrvftraqllqevwgyggtRTvDVhvRRlraklgpeydsmigtvrnvgykfvrps > 8hml_B interface=60,61,63,64,67,68,85, vgdlvieestytarlkgraleltykefellkylaqhagrvftraqllqevwgydffggtRTvDVhvRRlraklgpeydsmigtvRnvgykfvrps
interface signature	RTDVRR/RTDVRRR

Estimated binding specificities ?

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# IC=12.899 IC/col=0.759 n_of_columns=17

specificity:

A |   0   0   0  10  67   0   3  24  24  24  24   0   0   3   5  78   0
C |   0   0   0  12   6  96  73  24  24  24  24   0   0  10   3   9  96
G |   0  96   0  13  13   0  10  24  24  24  24   0  96   8   3   3   0
T |  96   0  96  61  10   0  10  24  24  24  24  96   0  75  85   6   0

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updated Thu Jan 8 02:18:29 2026