8hig_A : 3D-footprint complex

structure name	CO-CRYSTAL STRUCTURE OF C-TERMINAL DNA BINDING DOMAIN OF SACCHAROPOLYSPORA ERYTHRAEA GLNR IN COMPLEX WITH ITS COGNATE PROMOTER DNA (DNA-binding response OmpR family regulator)
reference	Zhang et al. 'To ? ? ?
source	Saccharopolyspora erythraea NRRL 2338
experiment	X-ray (resolution=2.33, R-factor=0.265)
structural superfamily	C-terminal effector domain of the bipartite response regulators;
sequence family	Transcriptional regulatory protein, C ter;
multimeric complexes	8hig_AB 8hml_AB
redundant complexes	8hml_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8hig_A interface=63,64,66,67,70,71, gdgmltvgdlvieestytarlkgraleltykefellkylaqhagrvftraqllqevwgyggtRTvDVhvRRlraklgpeydsmigtvrnvgykfvrps
interface signature	RTDVRR

Estimated binding specificities ?

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# IC=6.247 IC/col=0.892 n_of_columns=7

specificity:

A |   0   7   0   9  73   0   7
C |   0   9   0   7   7  96  73
G |   0  73   0   7   7   0   9
T |  96   7  96  73   9   0   7

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Dendrogram of similar interfaces ?

matrix format

  
  --RG--DTVT----STRG------WT----   L   +------------------------6lxn_A    
                                       ! 
  ------------------YG----------     --3                    +---3eyi_B    
                                       !      +-------------1 
  ------------RC--------KT------       +------2             +---2acj_B    
                                              ! 
  TT--KATT--QTTG----LTRT----FTYT   L          +-----------------2p7c_B

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updated Tue Jun 30 16:38:11 2026