interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HUMAN TFAP2A IN COMPLEX WITH DNA
(Transcription factor AP-2-alpha)
referenceXiao et al. 'Nucleic 51 8270 2023
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=0.164)
sequence familyTranscription factor AP2;
multimeric complexes8j0k_AB 8j0r_AB
reference complex8j0k_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAK

Estimated binding specificities ?

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# IC=3.527 IC/col=0.392 n_of_columns=9 specificity:   
A |  19  24  24  24  24  24   1   0   0
C |  19  24  24  24  24  24  19   0  96
G |  39  24  24  24  24  24  76  96   0
T |  19  24  24  24  24  24   0   0   0
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updated Sun Aug 3 01:15:26 2025