3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHUMAN HISTONE H2B VARIANT H2BFWT CRYO-EM STRUCTURE WITH 601 DNA SEQUENCE
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes8jcc_ABCDEFGH 8jcd_ABCDEFGH
redundant complexes8jcd
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  IT----------                                  +------3wkj_D    
                                +---------------6 
  ------RC----                  !               +------7yqk_C    
                                !  
  ------RT----                  !                      +7kbd_C    
                             +-11       +--------------2 
  ------RG----               !  !       !              +8upf_G    
                             !  !     +-7 
  ------RA--RA               !  !     ! !             +6a5l_g    
                             !  !     ! +-------------5 
  --HGRTRG----               !  +----10               +8rbx_V    
                             !        !  
  --------KG--               !        !                +7nkx_f    
                        +---12        +----------------1 
  ------RA----          !    !                         +7e9c_F    
                        !    !  
  ------RT----          !    !                        +7zs9_e    
                        !    !         +--------------4 
  ------RT----          !    !       +-8              +6px1_A    
                     +-13    !       ! ! 
  ------RG----       !  !    +-------9 +--------------7unc_a    
                     !  !            ! 
  ------RG----       !  !            !               +7ccr_A    
                   -14  !            +---------------3 
  ------RC----       !  !                            +7ux9_E    
                     !  !  
  --KT--------   L   !  +----------------------------7cvo_A    
                     !  
  ------RG----       +----------------------------7y7i_E    
                   

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updated Sun Jan 11 00:28:58 2026