3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHUMAN HISTONE H2B VARIANT H2BFWT CRYO-EM STRUCTURE WITH 601 DNA SEQUENCE
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes8jcc_ABCDEFGH 8jcd_ABCDEFGH
redundant complexes8jcd
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ------RA----       +-----------------------------6g0l_D    
                     !  
  IT----------       !                          +------3wkj_D    
                     !                      +---7 
  ----RG------       !                      !   +------5x0y_G    
                     !                +-----9 
  ----RA------       !                !     !         +1zla_C    
                     !           +---12     +---------4 
  ----RA----RA       !           !    !               +6a5l_g    
                     !           !    !  
  ----RG------       !     +----15    +----------------8jla_C    
                     !     !     !  
  ----RT------       !     !     !                     +7kbd_C    
                     !     !     +---------------------1 
  ----RG------     -19     !                           +8ox0_C    
                     !     !  
  --------KG--       !     !                         +---7nkx_f    
                     !     !       +-----------------5 
  ----RG------       !     !       !                 +---7unc_a    
                     !     !       !  
  ----RC------       !  +-17       !                  +---7xyf_B    
                     !  !  !       !            +-----6 
  ----RG------       !  !  !       !            !     +---6iy2_A    
                     !  !  !       !         +--8 
  ----RC------       !  !  !  +---14         !  !         +3kwq_E    
                     !  !  !  !    !         !  +---------2 
  ----RT------       !  !  !  !    !      +-10            +8grq_A    
                     !  !  !  !    !      !  !  
  ----RG------       !  !  !  !    !      !  !            +7ccr_A    
                     +-18  !  !    !   +-11  +------------3 
  ----RT------          !  +-16    !   !  !               +8hr1_E    
                        !     !    +--13  !  
  ----RC------          !     !        !  +---------------4xzq_E    
                        !     !        !  
  ----RT------          !     !        +-----------------7zs9_e    
                        !     !  
  --KT--------   L      !     +--------------------------7cvo_A    
                        !  
  ----RG------          +----------------------------7y7i_E    
                   

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updated Mon Aug 4 01:21:40 2025