8jkq_DG : 3D-footprint complex

structure name	T95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GACA MOTIF
reference	Wang et al. Structure 31 1441 2023
source	Homo sapiens
experiment	X-ray (resolution=3.09, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8jkq_D interface=74,77,78,82, ngklrqwlidqidsgkyplvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCalnKsndfeelversqldisdpykvyrivp > 8jkq_G interface=73,76,77,78,81, gklrqwlidqidsgkypglvweneeksifripwkhakqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCAlnKsndfeelversqldisdpykvyrivpe
interface signature	RRCK/RRCAK

Estimated binding specificities ?

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# IC=11.070 IC/col=1.006 n_of_columns=11

specificity:

A |   0  10  81  12  85   0   0   5  90   0  96
C |   0  12   5  69   6  96  96   5   5   0   0
G |   0  64   5   5   5   0   0  81   1  96   0
T |  96  10   5  10   0   0   0   5   0   0   0

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updated Thu Jan 8 04:07:27 2026