8jkq_DG : 3D-footprint complex

structure name	T95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GACA MOTIF
reference	Wang et al. Structure 31 1441 2023
source	Homo sapiens
experiment	X-ray (resolution=3.09, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8jkq_D interface=74,77,78,82, ngklrqwlidqidsgkyplvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCalnKsndfeelversqldisdpykvyrivp > 8jkq_G interface=73,76,77,78,81, gklrqwlidqidsgkypglvweneeksifripwkhakqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCAlnKsndfeelversqldisdpykvyrivpe
interface signature	RRCK/RRCAK

Estimated binding specificities ?

readout + contact

# IC=10.077 IC/col=0.916 n_of_columns=11

specificity:

A |   0   0   6   6   0   0   6   6   6  24  96
C |   0  96   6  78   0   0   6   6   6  24   0
G |   0   0   6   6  96  96   6  78   6  24   0
T |  96   0  78   6   0   0  78   6  78  24   0

scan!

home
updated Fri Aug 1 12:38:02 2025