8jkq_DG : 3D-footprint complex

structure name	T95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GACA MOTIF
reference	Wang et al. Structure 31 1441 2023
source	Homo sapiens
experiment	X-ray (resolution=3.09, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8jkq_D interface=74,77,78,82, ngklrqwlidqidsgkyplvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCalnKsndfeelversqldisdpykvyrivp > 8jkq_G interface=73,76,77,78,81, gklrqwlidqidsgkypglvweneeksifripwkhakqdynreedaalfkawalfkgkfregidkpdpptwkRrlRCAlnKsndfeelversqldisdpykvyrivpe
interface signature	RRCK/RRCAK

Estimated binding specificities ?

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# IC=11.334 IC/col=1.030 n_of_columns=11

specificity:

A |   0  10  85  10  81   0   0   5  90   0  96
C |   0  10   6  69   5  96  96   5   6   0   0
G |   0  74   0   5   5   0   0  81   0  96   0
T |  96   2   5  12   5   0   0   5   0   0   0

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updated Mon Dec 16 05:46:23 2024