interface graph thumbnail
legend  pdf

structure nameT95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GACA MOTIF
referenceWang et al. Structure 31 1441 2023
sourceHomo sapiens
experimentX-ray (resolution=3.09, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRCK/RRCAK

Estimated binding specificities ?

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# IC=11.053 IC/col=1.005 n_of_columns=11 specificity:   
A |   0  10  85  10  80   0   0   5  90   0  96
C |   0  10   1  71   6  96  96   5   6   0   0
G |   0  64   5   5   5   0   0  80   0  96   0
T |  96  12   5  10   5   0   0   6   0   0   0
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updated Sat Jun 27 13:41:33 2026