8jkq_FH : 3D-footprint complex

structure name	T95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GACA MOTIF
reference	Wang et al. Structure 31 1441 2023
source	Homo sapiens
experiment	X-ray (resolution=3.09, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8jkq_F interface=69,70,74, ngklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkdpptwkrlRCalnKsndfeelversqldisdpykvyrivp > 8jkq_H interface=78,79,82, gklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkrrlrCAlnKsndfeelversqldisdpykvyrivpe
interface signature	RCK/CAK

Estimated binding specificities ?

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# IC=6.431 IC/col=0.585 n_of_columns=11

specificity:

A |   0   0  17  24  24   0   0  24  24  17  80
C |   0  96  19  24  24   0   0  24  24  43   0
G |   0   0   8  24  24  96   0  24  24  19   8
T |  96   0  52  24  24   0  96  24  24  17   8

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updated Mon Dec 16 05:46:33 2024