interface graph thumbnail
legend  pdf

structure nameT95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GAGA MOTIF
referenceWang et al. Structure 31 1441 2023
sourceHomo sapiens
experimentX-ray (resolution=3.30, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRCK/HRRCAK

Estimated binding specificities ?

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# IC=11.139 IC/col=1.013 n_of_columns=11 specificity:   
A |   0   0   5   5   0   0   5   0   6   6  80
C |   0  96   5  80   0   0   5  96   5  80   6
G |   0   0   5   5  96  96   5   0   5   5   5
T |  96   0  81   6   0   0  81   0  80   5   5
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updated Thu Sep 12 03:50:46 2024