interface graph thumbnail
legend  pdf

structure nameT95R MUTANT IRF4 DNA-BINDING DOMAIN BOUND TO AN DNA CONTAINING GAGA MOTIF
referenceWang et al. Structure 31 1441 2023
sourceHomo sapiens
experimentX-ray (resolution=3.30, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRCK/HRRCAK

Estimated binding specificities ?

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# IC=10.992 IC/col=0.999 n_of_columns=11 specificity:   
A |   0   4  81   7  96   0  11   9  81   0  96
C |   0   4   7   4   0  96  76   6   4   0   0
G |   0  81   4  81   0   0   0  72   4  96   0
T |  96   7   4   4   0   0   9   9   7   0   0
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updated Thu Jan 8 04:08:03 2026