8kgm_AB : 3D-footprint complex

structure name	STRUCTURE OF AFRICAN SWINE FEVER VIRUS TOPOISOMERASE II IN COMPLEX WITH DSDNA
experiment	NMR
structural superfamily	Type II DNA topoisomerase;
reference complex	8j9v_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8kgm_A interface=462,536,694,695,745,788,840,841,846, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsvdvdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaieRQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh > 8kgm_B interface=467,541,699,700,750,793,845,846,851, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsiskkdnhvdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaieRQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh
interface signature	VKRQMRNPK/VKRQMRNPK

Estimated binding specificities ?

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# IC=12.090 IC/col=0.806 n_of_columns=15

specificity:

A |  96   0   0   0   8  11  66   8  24  24  74  15  96   0  96
C |   0   0   0   0   9  10  11   8  24  24   8   8   0  96   0
G |   0   0  96   0  71  11  11   9  24  24   6  11   0   0   0
T |   0  96   0  96   8  64   8  71  24  24   8  62   0   0   0

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updated Fri Aug 1 13:36:38 2025