8kgn_AB : 3D-footprint complex

structure name	STRUCTURE OF AFRICAN SWINE FEVER VIRUS TOPOISOMERASE II IN COMPLEX WITH DSDNA
experiment	NMR
structural superfamily	Type II DNA topoisomerase;
reference complex	8j9v_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8kgn_A interface=471,545,704,754,797,849,850,855, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsiskkdnhkqvdvdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaierQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh > 8kgn_B interface=461,535,693,694,744,787,839,840,845, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsisdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaieRQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh
interface signature	VKQMRNPK/VKRQMRNPK

Estimated binding specificities ?

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# IC=12.089 IC/col=0.756 n_of_columns=16

specificity:

A |  90   0   0   0  14  11  74  24  24  11  74  24  96   0  96   9
C |   2   0   0   0   0  11   9  24  24   9   4  24   0  96   0  70
G |   2   0  96   0  72  11   6  24  24  13  11  24   0   0   0   7
T |   2  96   0  96  10  63   7  24  24  63   7  24   0   0   0  10

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updated Sat Jun 27 14:50:40 2026