8kgn_AB : 3D-footprint complex

structure name	STRUCTURE OF AFRICAN SWINE FEVER VIRUS TOPOISOMERASE II IN COMPLEX WITH DSDNA
experiment	NMR
structural superfamily	Type II DNA topoisomerase;
reference complex	8j9v_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8kgn_A interface=471,545,704,754,797,849,850,855, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsiskkdnhkqvdvdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaierQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh > 8kgn_B interface=461,535,693,694,744,787,839,840,845, afeisdfkehakkksmwagalnkvtisglmgvftededlmalpihrdhcpallkifdeiivnatdherachnktkkvtyikisfdkgvfscendgpgipiakheqasliakrdvyvpevaschflagtninkakdcikggtngvglklamvhsqwailttadgaqkyvqhinqrldiiepptitpsremftrielmpvyqelgyaeplseteqadlsawiylracqcaayvgkgttiyyndkpcrtgsvmalakmytllsapnstihtatikadakpyslhplqvaavvspkfkkfehvsvingvncvkgehvtflkktinemvvkkfqqtikdknrkttlrdscsnifivivgsipgiewtgqrkdelsiaenvfkthysipssfltsmtksivdillqsisdkytrarnaggkraqdcmllaaegdsalsllrtgltlgksnpsgpsfdfcgmislggVimnackkvtnittdsgetimvrneqltnnkvlqgivqvlgldfnchyktqeeraklrygcivacvdqdldgcgKilglllayfhlfwpqliihgfvkrlltplirvyekgktmpvefyyeqefdawakkqtslanhtvkyykglaahdthevksmfkhfdnmvytftlddsakelfhiyfggeselrkrelctgvvpltetqtqsihsvrripcslhlqvdtkaykldaieRQipnfldgmtrarrkilaggvkcfasnnrerkvfqfggyvadhmfyhhgdMslntsiikaaqyypgsshlypvfigigsfgsrhlggkdagspRyisvqlasefiktmfpaedswllpyvfedgqraepeyyvpvlplaimeygaNPsegwKyttwarqledilalvrayvdkdnpkhellhyaikhkitilplrpsnynfkghlkrfgqyyysygtyviseqrniititelplrvptvayiesikkssnrmtfieeiidysssetieilvklkpnslnriveefketeeqdsienflrlrnclhshlnfvkpkggiiefntyyeilyawlpyrrelyqkrlmrehavlklriimetaivryinesaelnlshyedekeasrilsehgfpplnhtliispefasieelnqkalqgcytyilslqarelliaaktrrvekikkmqarldkveqllqespfpgasvwleeidavekaiikgrntqwkfh
interface signature	VKQMRNPK/VKRQMRNPK

Estimated binding specificities ?

readout + contact

# IC=13.086 IC/col=0.818 n_of_columns=16

specificity:

A |   5   0   0   0  65   3  65  24  24   5  78   9  96   0  96   0
C |   8   0   0   0  11   8   9  24  24  10   8  65   0  96   0   0
G |  78   0  96   0   9   7  11  24  24   7   5  11   0   0   0   2
T |   5  96   0  96  11  78  11  24  24  74   5  11   0   0   0  94

scan!

home
updated Fri Aug 1 13:38:25 2025