interface graph thumbnail
legend  pdf

structure nameTWIST1-TCF4-ALX4 COMPLEX ON SPECIFIC DNA
referenceMorgunova et al. Cell 187 692 2024
experimentX-ray (resolution=2.90, R-factor=0.223)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes8osb_ABE
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNRER

Estimated binding specificities ?

contactlogo
# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0   0  13  13
C |   0   0  13  16
G |   0  96  16  54
T |  96   0  54  13
scan!

home
updated Wed Dec 18 18:57:22 2024