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structure nameDNA BINDING DOMAIN OF HNF-1A BOUND TO P2-HNF4A PROMOTER DNA VARIANT (P2 -181G>T)
referenceMyllykoski et al. 'JCI 9 ? 2024
sourceHomo sapiens
experimentX-ray (resolution=2.80, R-factor=?)
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNQSHSQTRYNK/NQSHQRYNNK

Estimated binding specificities ?

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# IC=13.803 IC/col=0.920 n_of_columns=15 specificity:   
A |   0   0  96  80  71  24  96   0   0  96  96  81   5  24  12
C |   0   0   0   5   5  24   0   0   0   0   0   5  80  24  10
G |   0   0   0   6  10  24   0  96   0   0   0   5   5  24  64
T |  96  96   0   5  10  24   0   0  96   0   0   5   6  24  10
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updated Thu Sep 12 06:14:10 2024