8q63_AB : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF IC8', A SECOND STATE OF YEAST MITOCHONDRIAL RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH 8-MER RNA, PPPGPGPUPAPAPAPUPG
experiment	NMR
structural superfamily	DNA/RNA polymerases;S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6ymv_A 6ymv_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8q63_A interface=135,142,144,145,148,171,217,218,219,221,222,371,375,400,404,595,597,598,599,600,605,702,711,712,713,724,736,810, inffeiynslptleekkafesalnifnqdrqkvlenrateaarerwkhdfeeakargdisieknlnvklwkwynemlplvkeeinhcrsllseklsdkkglnkvdtnrlgygpyltlidpgkmcvitilellklNstgegmRtARavIsvgkaiemefrseqvlkkilwpQsirarigsvlismliqvakvsvqgvdpvtkakvhgeapafahgyqYHNgSKlgvlkihktlirqlngerliasvqpqllpmlvepkpwvnwrsggyhytqstllrtkdspeqvaylkaasdngdidrvydglnvlgrtpwtvnrkvfdvvsqvwnkgegfldipgaqdemvlppapppsilrawklqvktiankfssdrSnrcDtnykleiaraflgeklyfphnldfRgraYplsphfnhlgndmsrgllifwhgkklgpsglkwlkihlsnlfgfdklplkdrvafteshlqdikdsaenpltgdrwwttadkpwqalatcfelnevmkmdnpeefishqpvhqdgtcnglqhyaalggdvegatqvnlvpsdkpqdvyahvarlvqkrleiaaekgdenakilkdkitrkvvkqtvmtnvYgVTYVgatfQiakqlspifddrkesldfskyltkhvfsairelfhsahliqdwlgesakrisksirldvdeksfkngnkpdfmssviwttplglpivqpyreeskkQvetnlqtvFISdpfavnpvnaRrqkaglppnfiHsldashmllsaaecgkqgldfasvhdsywthasdidtmnvvlreqfiklhevdlvlrlkeefdqryknyvkigKlkrstdlaqkiirirkdlsrklgrsttladeiyfekkrqellnspliedrnvgekmvttvslfeditdldalegmsvllplrlpeippkgdfdvtvlrnsqyffs > 8q63_B interface=17,100,102,103,104,143,147,148, svpipgikdisklkffYgfkylwnptvynkifdkldltktykhpeelkvldlypgvgiqsaifynkycprqysllekrsslykflnakfegsplqilkrDpYDWstysnlideerifvpevqssdhindkfltvanvtgegsEgliMQwlscignknwlyrfgkvkmllwmpsttarkllarpgmhsrskcsvvreaftdtkliaisdanelkgfdsqcieewdpilfsaaeiwptkgkpialvemdpidfdfdvdnwdyvtrhlmilkrtplntvmdslghggqqyfnsritdkdllkkcpidltndefiyltklfmewpfkpdilmd
interface signature	NRARIQYHNSKSDRYYVTYVQQFISRHK/YDYDWEMQ

Estimated binding specificities ?

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# IC=17.474 IC/col=0.760 n_of_columns=23

specificity:

A |   0  96   0  96  96   0   0  96  62   4  24  24  24  14   0   0  82  69  24  24  24  24   0
C |   0   0   0   0   0   0   0   0  13   4  24  24  24   8   0  96   4   8  24  24  24  24  96
G |   0   0   0   0   0  96   0   0   8   4  24  24  24  13  96   0   6   6  24  24  24  24   0
T |  96   0  96   0   0   0  96   0  13  84  24  24  24  61   0   0   4  13  24  24  24  24   0

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updated Thu Jan 8 07:44:38 2026